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The Screwworm Eradication Program Records, housed in Special Collections of the National Agricultural Library (NAL), documents one of the greatest success stories in the history of American agriculture. Led by the United States Department of Agriculture (USDA), the eradication of the screwworm from the United States, Mexico, and most of Central America marked a major victory over the destruction of domestic and wild animals by an insect which feeds only on the living tissue of warm-blooded animals.

The Screwworm Eradication Program Records document research and eradication efforts from the 1930s through 2000. These materials include correspondence, plans, reports, scientific papers and manuscripts, publications, raw research data and research analyses, livestock producer information materials and reports, cooperative agreements, photographs, maps and artifacts.